BDBM523463 (+/-)-{[2-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-1-(2-chlorophenyl)ethyl]sulfanyl}acetic Acid (Racemate)::US11136296, Example 194

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)NCC(SCC(O)=O)c1ccccc1Cl)-c1ccccc1

InChI Key InChIKey=ZXIWBUUBMSPRTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523463   

TargetProstaglandin F2-alpha receptor(Human)
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US Patent
LigandPNGBDBM523463(US11136296, Example 194 | (+/-)-{[2-{[(6-Bromo-3-m...)
Affinity DataIC50: 7.90nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent