BDBM532288 N-(2,6-dimethylphenyl)-2-(2-methyl-4-piperazin-1-yl-anilino)-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide::US11208696, Example 7::WITJ0416/WITJ429A

SMILES Cc1cccc(C)c1NC(=O)c1ccn-2c1CCc1cnc(Nc3ccc(cc3C)N3CCNCC3)nc-21

InChI Key InChIKey=AGPXGQNJJJOBLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532288   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532288(N-(2,6-dimethylphenyl)-2-(2-methyl-4-piperazin-1-y...)
Affinity DataIC50:  0.700nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent