BDBM533556 US11225475, Compound 3

SMILES Cc1nc2CN(Cc2s1)C(=O)Nc1nc(ccc1N)-c1ccc(F)cc1F

InChI Key InChIKey=MCOVSZOJAIYMSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533556   

TargetHistone deacetylase 1(Human)
Alkermes

US Patent
LigandPNGBDBM533556(US11225475, Compound 3)
Affinity DataIC50: 300nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Alkermes

US Patent
LigandPNGBDBM533556(US11225475, Compound 3)
Affinity DataIC50: 2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent