BDBM541365 US11267803, Example 13

SMILES NC(=O)C(=O)C1(CCCCC1)NC(=O)[C@@H]1C[C@@H](CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)n1nncc1CNS(=O)(=O)C1CC1

InChI Key InChIKey=AHSBHBQNVCSTGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 541365   

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM541365(US11267803, Example 13)
Affinity DataIC50: 17.2nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent