BDBM557822 1-[4-[5-fluoro-6-[5-[[6-(1-fluoro-1-methyl-ethyl)pyrazin-2-yl]amino]-1-methyl-pyrazol-4-yl]-3-pyridyl]phenyl]cyclopropanecarboxylic Acid Hydrochloride::US11365185, Example 4B
SMILES Cn1ncc(c1Nc1cncc(n1)C(C)(C)F)-c1ncc(cc1F)-c1ccc(cc1)C1(CC1)C(O)=O
InChI Key InChIKey=VQHYQHISOUPKFU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 557822
Affinity DataKi: 80.5nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
Affinity DataIC50: 16.7nMAssay Description:A cDNA encoding the human LPAR1 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U937 cells using Lipo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair