BDBM557825 1-[4-[6-[5-[(6-isopropoxypyrazin-2-yl)amino]-1-methyl-pyrazol-4-yl]-3-pyridyl]-2-methyl-phenyl]cyclopropanecarboxylic Acid; Hydrochloride::US11365185, Example 7B
SMILES CC(C)Oc1cncc(Nc2c(cnn2C)-c2ccc(cn2)-c2ccc(c(C)c2)C2(CC2)C(O)=O)n1
InChI Key InChIKey=KAPVSPYBFCBQPD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 557825
Affinity DataKi: 72.3nMAssay Description:The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-...More data for this Ligand-Target Pair
Affinity DataIC50: 27.1nMAssay Description:A cDNA encoding the human LPAR1 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U937 cells using Lipo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair