BDBM560009 US11377438, Example 56

SMILES C[C@@H]1CCCN(C1)c1ncc(cc1C(=O)Nc1ccnc(c1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=GXIQLIKRDHIRNL-LLVKDONJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560009   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560009(US11377438, Example 56)
Affinity DataIC50:  9.10nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent