BDBM571953 2-{[(alphaR)-6-{4- [(3,3-difluorocyclo- butyl)methyl]-2,5- dioxoimidazolidin- 1-yl}spiro[3.3]- heptan-2-yl]oxy}- pyridine-3-carbox- amide::US11447487, Example 46

SMILES NC(=O)c1cccnc1O[C@H]1C[C@]2(C1)C[C@@H](C2)N1C(=O)NC(CC2CC(F)(F)C2)C1=O

InChI Key InChIKey=YKMQWNBHBXTASQ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571953   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571953(2-{[(alphaR)-6-{4- [(3,3-difluorocyclo- butyl)meth...)
Affinity DataIC50: 48nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent