BDBM575916 (6-{3-[endo-3- amino-8- azabicyclo [3.2.1]octan- 8-yl]-5H-pyrrolo [2,3-b]pyrazin-7- yl}-7-chloro- 1,3-benzothiazol- 2-yl)methanol, hydrochloride salt::US11466016, Example 44

SMILES N[C@@H]1C[C@@H]2CC[C@H](C1)N2c1cnc2c(c[nH]c2n1)-c1ccc2nc(CO)sc2c1Cl

InChI Key InChIKey=MLVPTSRHNAPRHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575916   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM575916(US11466016, Example 44 | (6-{3-[endo-3- amino-8- a...)
Affinity DataIC50: 6.80nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2022
Entry Details
US Patent