BDBM578519 (S)-3-methoxy- 5,5-dimethyl-3- (5-methylthiazol- 4-yl)-6- oxocyclohex-1- enecarbonitrile::US11479539, Compound 38

SMILES CO[C@]1(CC(C)(C)C(=O)C(=C1)C#N)c1ncsc1C

InChI Key InChIKey=JQEZTOFDGXJICR-CQSZACIVSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578519   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578519((S)-3-methoxy- 5,5-dimethyl-3- (5-methylthiazol- 4...)
Affinity DataEC50:  132nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent