BDBM578539 7-methoxy-4-7- (4-methyl-1,3- thiazol-2-yl)-4- oxospiro[2.5]oct- 5-ene-5- carbonitrile (Enantiomer A)::US11479539, Compound 140::US11479539, Compound 59
SMILES COC1(CC2(CC2)C(=O)C(=C1)C#N)c1nc(C)cs1
InChI Key InChIKey=SFYUNAHVSUWDJA-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 578539
Affinity DataEC50: 261nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair