BDBM580431 US11498926, Example 181A

SMILES CN[C@H]1CCN(C1)c1nc2ccc(-c3c(C)noc3C)c3OC[C@@H](c4ccccn4)n1c23

InChI Key InChIKey=JHYIBUDFHJSKHT-JXFKEZNVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 580431   

TargetBromodomain-containing protein 4 [353-454](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM580431(US11498926, Example 181A)
Affinity DataIC50: <100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [58-164](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM580431(US11498926, Example 181A)
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent