BDBM587529 4-((7-chloro-3-methyl- 2,4-dioxo-3,4- dihydroquinazolin- 1(2H)-yl)methyl)-N- hydroxybenzamide::US11535598, Compound 10

SMILES Cn1c(=O)n(Cc2ccc(cc2)C(=O)NO)c2cc(Cl)ccc2c1=O

InChI Key InChIKey=UZJXRINUSKWWFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587529   

TargetHistone deacetylase 1(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM587529(4-((7-chloro-3-methyl- 2,4-dioxo-3,4- dihydroquina...)
Affinity DataIC50:  2.72E+3nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM587529(4-((7-chloro-3-methyl- 2,4-dioxo-3,4- dihydroquina...)
Affinity DataIC50:  4nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Annji Pharmaceutical

US Patent
LigandPNGBDBM587529(4-((7-chloro-3-methyl- 2,4-dioxo-3,4- dihydroquina...)
Affinity DataIC50:  523nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent