BDBM592996 US11578054, Example 1018

SMILES CC(=O)NC1CCN(CCCOc2cccc(c2Cl)-c2cccc3C(CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H](CCO)C(O)=O)cc2Cl)CC1

InChI Key InChIKey=NCNKKFXRMYWWPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592996   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM592996(US11578054, Example 1018)
Affinity DataIC50: 2.90nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent