BDBM601982 US11643417, Ex. No. 14::US11643417, Ex. No. 15::US11643417, Ex. No. 47

SMILES OCC1CCOC(C1)C(F)(F)CN1CCNC(=O)c2oc3ccc(cc3c12)C(F)(F)F

InChI Key InChIKey=RUVCYNVUILWPGN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 601982   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM601982(US11643417, Ex. No. 14 | US11643417, Ex. No. 15 | ...)
Affinity DataKi:  0.0250nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM601982(US11643417, Ex. No. 14 | US11643417, Ex. No. 15 | ...)
Affinity DataKi:  0.0290nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM601982(US11643417, Ex. No. 14 | US11643417, Ex. No. 15 | ...)
Affinity DataKi:  0.0330nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent