BDBM626355 2-[[[4-cyano-7-[4-(pentafluoro- lambda6-sulfanyl)phenyl]-2,3- dihydrobenzofuran-5- yl]amino]methyl]prop-2- enehydroxamic acid::US11787775, Compound 38
SMILES ONC(=O)C(=C)CNc1cc(c2OCCc2c1C#N)-c1ccc(cc1)S(F)(F)(F)(F)F
InChI Key InChIKey=DGLKNRDFMZDACB-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 626355
Affinity DataIC50: 90nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-3/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 160nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 100nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-4/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 50nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-5/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 970nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair