BDBM649684 3-((4-((3′-(3-(4-(((2-carboxyethyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propoxyl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)methoxy)-5-chloro-2-methoxybenzyl)amino)propionic acid::US20240043392, Compound II-12

SMILES COc1cc(OCc2cccc(c2C)-c2cccc(OCCCn3cc(CNCCC(O)=O)nn3)c2C)c(Cl)cc1CNCCC(O)=O

InChI Key InChIKey=OCJGTGOPIGCGPB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649684   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649684(3-((4-((3′-(3-(4-(((2-carboxyethyl)amino)met...)
Affinity DataIC50: 5nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649684(3-((4-((3′-(3-(4-(((2-carboxyethyl)amino)met...)
Affinity DataKd:  50nMAssay Description:The test compound was dissolved in DMSO to make a stock solution with a final concentration of 10 mM, then diluted to 1× with 1.05× PBS-P+, and then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent