BDBM66480 4,5-bis(chloranyl)-2-[(3,5-dimethylphenyl)methyl]pyridazin-3-one::4,5-dichloro-2-(3,5-dimethylbenzyl)pyridazin-3-one::4,5-dichloro-2-[(3,5-dimethylphenyl)methyl]-3-pyridazinone::4,5-dichloro-2-[(3,5-dimethylphenyl)methyl]pyridazin-3-one::MLS000390370::SMR000255337::cid_2585288

SMILES Cc1cc(C)cc(Cn2ncc(Cl)c(Cl)c2=O)c1

InChI Key InChIKey=LQCNMWUGGBGOSX-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 66480   

TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM66480(SMR000255337 | cid_2585288 | 4,5-bis(chloranyl)-2-...)
Affinity DataIC50: 1.17E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66480(SMR000255337 | cid_2585288 | 4,5-bis(chloranyl)-2-...)
Affinity DataEC50:  2.17E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66480(SMR000255337 | cid_2585288 | 4,5-bis(chloranyl)-2-...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay