BDBM6650 1-benzyl-3-(7-hydroxynaphthalen-1-yl)urea::CHEMBL139989::Diarylurea deriv. 1e::N-Benzyl-N -(7-hydroxy-1-naphthyl)urea
SMILES Oc1ccc2cccc(NC(=O)NCc3ccccc3)c2c1
InChI Key InChIKey=NTZXOVWJUVTXIF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 6650
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Binding affinity towards cloned human vanilloid receptor subtype 1 in HEK293 cell membranes using [3H]-RTX as radioligandMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute
Banyu Tsukuba Research Institute
Affinity DataIC50: 4.10E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Dislacement of [3H]-RTX binding to human vanilloid receptor subtype 1 expressed in HEK293 cell membranes (inactive)More data for this Ligand-Target Pair