BDBM70 DMPC Cyclic Urea 50::N-{5-[(4R,5S,6S,7R)-4,7-dibenzyl-3-{5-[(4-fluorophenyl)formamido]pentyl}-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]pentyl}-4-fluorobenzamide
SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(CCCCCNC(=O)c2ccc(F)cc2)C(=O)N(CCCCCNC(=O)c2ccc(F)cc2)[C@@H]1Cc1ccccc1
InChI Key InChIKey=VMAACENPBLBGNM-WESAGZJESA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 70
Affinity DataKi: 18nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 18nM ΔG°: -11.0kcal/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair