BDBM7723 (3Z)-N-[3-(1H-imidazol-1-yl)propyl]-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indole-5-carboxamide::3-{[4-(Aminosulfonyl)phenyl]hydrazono}-N-[3-(1H-imidazol-1-yl)propyl]-2-oxo-2,3-dihydro-1H-indole-5-carboxamide::Oxindole-Based Inhibitor 59

SMILES NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc(cc23)C(=O)NCCCn2ccnc2)cc1

InChI Key InChIKey=ADGOSWMTFHSWDE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7723   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7723((3Z)-N-[3-(1H-imidazol-1-yl)propyl]-2-oxo-3-[2-(4-...)
Affinity DataIC50:  230nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7723((3Z)-N-[3-(1H-imidazol-1-yl)propyl]-2-oxo-3-[2-(4-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7723((3Z)-N-[3-(1H-imidazol-1-yl)propyl]-2-oxo-3-[2-(4-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7723((3Z)-N-[3-(1H-imidazol-1-yl)propyl]-2-oxo-3-[2-(4-...)
Affinity DataIC50:  25nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed