BDBM783717 US20250333394, Example 19

SMILES C[C@@H]1CN(c2ncc(C(C)(C)O)cn2)CCN1C(=O)[C@H]1C[C@@H](Cc2c[nH]c(=O)c(C(F)(F)F)c2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783717   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Abbvie

US Patent
LigandPNGBDBM783717(US20250333394, Example 19)
Affinity DataIC50: 5.79nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbvie

US Patent
LigandPNGBDBM783717(US20250333394, Example 19)
Affinity DataIC50: 6.75E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent