BDBM783722 US20250333394, Example 24

SMILES C[C@@H]1CN(C(=O)C2CC(C3C=C(C(F)(F)F)C(=O)NC3)C2)C[C@H](C)N1c1ncc(C(F)(F)F)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783722   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Abbvie

US Patent
LigandPNGBDBM783722(US20250333394, Example 24)
Affinity DataIC50: 1.87E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbvie

US Patent
LigandPNGBDBM783722(US20250333394, Example 24)
Affinity DataIC50: 3.08E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent