BDBM783725 US20250333394, Example 27

SMILES CC(C)(O)C1C=NC(N2CCN(C(=O)C3CC(CC4C=C(C(F)(F)F)C(=O)NC4)C3)CC2)=NC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783725   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Abbvie

US Patent
LigandPNGBDBM783725(US20250333394, Example 27)
Affinity DataIC50: 2.34nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbvie

US Patent
LigandPNGBDBM783725(US20250333394, Example 27)
Affinity DataIC50: 231nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent