BDBM8584 (3-Pyridylmethylene)tetrahydronaphthalene 3a::3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemethyl]pyridine::3-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]pyridine Hydrochloride

SMILES C1C\C(=C/c2cccnc2)c2ccccc2C1

InChI Key InChIKey=GCIGECZMYPPCHH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8584   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8584(3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8584(3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 715nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Calcutta

Curated by ChEMBL
LigandPNGBDBM8584(3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAromatase(Human)
University of Calcutta

Curated by ChEMBL
LigandPNGBDBM8584(3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 6.58E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Calcutta

Curated by ChEMBL
LigandPNGBDBM8584(3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed