BDBM87148 CHEMBL1254908::N-[2-[1-(3-chlorophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid::N-[2-[1-(3-chlorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoranyl-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[2-[1-(3-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid::VU0405265-1::cid_46938433
SMILES Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC2(CC1)N(CNC2=O)c1cccc(Cl)c1
InChI Key InChIKey=HRCANAIPZZVDRQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 87148
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 73nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 73nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair