BDBM87231 N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide::N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide (Inh_VU0285655-1)::N-[2-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide::N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-quinolinecarboxamide::N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide::VU0285655-1::cid_44138050
SMILES O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1cnc2ccccc2c1
InChI Key InChIKey=WJOCDBUFEUKYNI-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 87231
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 90nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 500nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.00E+4nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: >1.00E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 450nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.90E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair