BDBM50296350 (S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-hydroxyethylamino)-2-oxo-1,2-dihydropyridin-3-yl)-7-methyl-1H-benzo[d]imidazol-5-yl)piperazin-1-yl)propanenitrile::BMS-554417::CHEMBL564417

SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NC[C@@H](O)c2ccccc2Cl)cc[nH]c1=O)N1CCN(CCC#N)CC1

InChI Key InChIKey=SLFIVXXZOYCJGB-XMMPIXPASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296350   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350((S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-hydroxyethyla...)
Affinity DataIC50:  68nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350((S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-hydroxyethyla...)
Affinity DataIC50: >1.50E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350((S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-hydroxyethyla...)
Affinity DataIC50:  94nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50296350((S)-3-(4-(2-(4-(2-(2-chlorophenyl)-2-hydroxyethyla...)
Affinity DataIC50:  51nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed