BDBM50049244 5-{4-[2-(Benzooxazol-2-yl-methyl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione::BRL-48482::CHEMBL17805
SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1nc2ccccc2o1
InChI Key InChIKey=YDFXQSJZFCAXMK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50049244
Affinity DataKi: 22nMAssay Description:inhibition of [125I]-SB 236636 binding to human PPAR gamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of [125I]-SB 236636 binding to human PPAR gamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Activation of peroxisome proliferator activated receptor gamma measured by induction of 50% of maximum alkaline phosphatase activity, transfection as...Checked by AuthorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Mus musculus)
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:In vitro transcriptional activation of Peroxisome proliferator activated receptor gamma (PPAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair