BDBM50121328 CHEMBL3622090::US10562882, Example 35

SMILES CNc1cc(ccn1)C(=O)N1CCCC(F)(C1)c1ncc(Cl)cc1C

InChI Key InChIKey=KJJXBCYIKIOANE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121328   

TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50121328(CHEMBL3622090 | US10562882, Example 35)
Affinity DataIC50:  290nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50121328(CHEMBL3622090 | US10562882, Example 35)
Affinity DataIC50:  290nMAssay Description:Antagonist activity at human PKR1 expressed in rat RBL2H3 cells assessed as inhibition of PK1-stimulated intracellular calcium release incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed