BDBM50511409 Imanixil

SMILES CC1(C)CN(C(=O)N1)c1ncc(C(=O)Nc2cccc(c2)C(F)(F)F)c(N)n1

InChI Key InChIKey=FUSNOPLQVRUIIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511409   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human full length PI5P4Kalpha expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human full length PI5P4Kbeta expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after ...More data for this Ligand-Target Pair
In DepthDetails PubMed