BDBM532289 JGS439C::N-(2,6-dimethylphenyl)-2-[2-methoxy-4-(tetrahydropyran-4-ylcarbamoyl)anilino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide::US11208696, Example 8

SMILES COc1cc(ccc1Nc1ncc2CCc3c(ccn3-c2n1)C(=O)Nc1c(C)cccc1C)C(=O)NC1CCOCC1

InChI Key InChIKey=WRYZBCKSXQMHKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532289   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532289(JGS439C | N-(2,6-dimethylphenyl)-2-[2-methoxy-4-(t...)
Affinity DataIC50:  0.600nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent