BDBM50085656 CHEMBL3425540::US11419874, Example 12

SMILES Cc1nc2cccnc2n2c(nnc12)-c1ccccc1Cl

InChI Key InChIKey=DKNLSEAXHKQSJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085656   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Oslo University Hospital

US Patent
LigandPNGBDBM50085656(CHEMBL3425540 | US11419874, Example 12)
Affinity DataIC50:  15nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Oslo University Hospital

US Patent
LigandPNGBDBM50085656(CHEMBL3425540 | US11419874, Example 12)
Affinity DataIC50:  15nMAssay Description:Inhibition of 6-His-tagged human recombinant PDE2A expressed in Sf9 cells using [3H]cGMP incubated for 40 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed