BDBM23617 (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(4-nitrophenyl)methyl]sulfanyl}-9H-purin-9-yl)oxolane-3,4-diol::4-nitrobenzylmercaptopurine ribonucleoside::CHEMBL418509::NBMPR::NBTI::Nitrobenzylthioinosine
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccc(cc3)[N+]([O-])=O)ncnc12
InChI Key InChIKey=DYCJFJRCWPVDHY-LSCFUAHRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 23617
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.430nM ΔG°: -12.6kcal/mole IC50: 7.60nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.700nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in K562 cells after 45 mins by flow cytometryMore data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.700nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from human ENT1 transporter in human K562 cellsMore data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.700nMAssay Description:Binding affinity of compound towards Nucleoside transporter es-type by facile competitive binding flow cytometric assay using the human K562 chronic ...More data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.700nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from K562 cell nucleoside transporterMore data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometryMore data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataKi: 0.708nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii adenosine kinaseMore data for this Ligand-Target Pair
TargetSolute carrier family 28 member 3(Homo sapiens (Human))
University Of Tennessee Health Sciences Center
Curated by ChEMBL
University Of Tennessee Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 8.81E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataIC50: 8.51nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CNT2 (unknown origin)More data for this Ligand-Target Pair
TargetEquilibrative nucleoside transporter 1(Homo sapiens (Human))
University of Tennessee Health Science Center
University of Tennessee Health Science Center
Affinity DataIC50: 1nMAssay Description:Inhibition of ENT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Toxoplasma gondii adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CNT1 (unknown origin)More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute
Curated by ChEMBL
The Netherlands Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Toxoplasma gondii adenosine kinaseMore data for this Ligand-Target Pair