BDBM53407 2-(2-methoxyphenyl)-8-nitro-5-oxidanyl-chromen-4-one::5-hydroxy-2-(2-methoxyphenyl)-8-nitro-1-benzopyran-4-one::5-hydroxy-2-(2-methoxyphenyl)-8-nitro-chromone::5-hydroxy-2-(2-methoxyphenyl)-8-nitrochromen-4-one::MLS000518626::PiI::SMR000465235::cid_16060391

SMILES COc1ccccc1-c1cc(=O)c2c(O)ccc([N+]([O-])=O)c2o1

InChI Key InChIKey=IYMLMYHUJIUNLF-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53407   

TargetPeptidyl-prolyl cis-trans isomerase ESS1(Saccharomyces cerevisiae (Baker's yeast))
Tohoku University

LigandPNGBDBM53407(2-(2-methoxyphenyl)-8-nitro-5-oxidanyl-chromen-4-o...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Assay was carried out measuring the MCA fluorescence using Suc-Ala-Glu-Pro-Phe-MCA as substrate purchased from Japan Peptide Institute Co.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53407(2-(2-methoxyphenyl)-8-nitro-5-oxidanyl-chromen-4-o...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53407(2-(2-methoxyphenyl)-8-nitro-5-oxidanyl-chromen-4-o...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay