BDBM50037945 1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl]-4-methylsulfonylbenzene::1-[4,4-dimethyl-2-(4-methylsulfonylphenyl)-1-cyclopentenyl]-4-fluorobenzene::1-{4,4-dimethyl-2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}-4-fluorobenzene::CHEMBL89578::SC-58231

SMILES CC1(C)CC(=C(C1)c1ccc(cc1)S(C)(=O)=O)c1ccc(F)cc1

InChI Key InChIKey=VKUCTHVTLJBHDT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50037945   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  1.83E+4nMAssay Description:Compound was evaluated in vitro for the inhibitory activity against constitutive form of human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  1.83E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  15.1nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  15nMAssay Description:Compound was evaluated in vitro for the inhibitory activity against inducible form of human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  15nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed