BDBM50322731 2-(2-chloro-5-(trifluoromethyl)phenylamino)-2-oxo-1-phenylethyl 2-(3-methyl-4-nitrobenzamido)acetate::CHEMBL1171857::cid_4437145

SMILES Cc1cc(ccc1[N+]([O-])=O)C(=O)NCC(=O)OC(C(=O)Nc1cc(ccc1Cl)C(F)(F)F)c1ccccc1

InChI Key InChIKey=FHYGFHQBXJYJHC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322731   

TargetCruzipain(Trypanosoma cruzi)
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50322731(2-(2-chloro-5-(trifluoromethyl)phenylamino)-2-oxo-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as Z-Phe-Arg-aminomethylcoumarin cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50322731(2-(2-chloro-5-(trifluoromethyl)phenylamino)-2-oxo-...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay