BDBM50335910 CHEMBL1668776::yezoquinolide

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]-[#6]-1=[#6]-[#6@@H](-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6]-2=[#6]-[#6](=O)-[#6]=[#6](-[#6])-[#6]-2=O)-[#8]-[#6]-1=O

InChI Key InChIKey=PRJQMQHHBMRRQA-QWYAYQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335910   

TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335910(CHEMBL1668776 | yezoquinolide)
Affinity DataIC50:  5.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed