BDBM104485 US8586597, 99::USRE44599, 98

SMILES CCC(Nc1ncnc2nc[nH]c12)c1nc2ccccc2c(=O)n1-c1ccccc1

InChI Key InChIKey=ROIASNIEFPZNJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104485   

LigandPNGBDBM104485(US8586597, 99 | USRE44599, 98)
Affinity DataIC50:  16nMAssay Description:Compounds of the invention were tested for inhibitory activity and potency against PI3Kδ.More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM104485(US8586597, 99 | USRE44599, 98)
Affinity DataIC50:  16nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM104485(US8586597, 99 | USRE44599, 98)
Affinity DataIC50:  16nMAssay Description:Biochemical assay using PI3K delta.More data for this Ligand-Target Pair
In DepthDetails US Patent