BDBM112653 US9695181, IIa

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2nn(CCCCCCCC(=O)NO)c3ncnc(N)c23)c1

InChI Key InChIKey=PVZJLPGZMRIHCQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 112653   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Double Rider Medicine

US Patent
LigandPNGBDBM112653(US9695181, IIa)
Affinity DataIC50:  3nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Double Rider Medicine

US Patent
LigandPNGBDBM112653(US9695181, IIa)
Affinity DataIC50:  1.09nMT: 2°CAssay Description:Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Double Rider Medicine

US Patent
LigandPNGBDBM112653(US9695181, IIa)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent