BDBM116900 US8637532, 626

SMILES COc1ccc(cc1)C(=O)Nc1cccc(CNc2ncnc3c(cc(CN4CCOCC4)cc23)C(N)=O)c1

InChI Key InChIKey=OEDBLXPEGILSSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 116900   

TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116900(US8637532, 626)
Affinity DataIC50:  9.90E+3nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116900(US8637532, 626)
Affinity DataIC50:  140nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116900(US8637532, 626)
Affinity DataIC50:  27nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In DepthDetails US Patent