BDBM11902 (2S)-2-(adamantan-1-yl)-2-amino-N-(1-cyano-1-methylethyl)acetamide::seco-proline-based inhibitor 18
SMILES [H][C@@](N)(C(=O)NC(C)(C)C#N)[C@@]12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=LQRSXZPMVCAXFW-IHCLACGKSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 11902
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair