BDBM12187 2-(3,4-difluorophenyl)-1,2,3,4-tetrahydroisoquinoline::isoquinoline derivative 10

SMILES Fc1ccc(cc1F)N1CCc2ccccc2C1

InChI Key InChIKey=RTLGDLOKGBZEJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12187   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12187(2-(3,4-difluorophenyl)-1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12187(2-(3,4-difluorophenyl)-1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM12187(2-(3,4-difluorophenyl)-1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed