BDBM141867 US8921410, Table 1 Compound 33

SMILES Brc1cc(oc1Br)C(=O)N1CC2CNCC2C1

InChI Key InChIKey=UXIXSVLZTCKWCM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141867   

TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141867(US8921410, Table 1 Compound 33)
Affinity DataKi:  4.90nM ΔG°:  -11.2kcal/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141867(US8921410, Table 1 Compound 33)
Affinity DataKi:  20nM ΔG°:  -10.4kcal/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent