BDBM15320 6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-chlorophenyl}-5-methyl-2,3,4,5-tetrahydropyridazin-3-one::dihydropyridazinone 14n

SMILES CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1Cl

InChI Key InChIKey=MPIGBQZXCYUSDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15320   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112](Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15320(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-c...)
Affinity DataIC50:  46nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15320(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-c...)
Affinity DataIC50:  4.80nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed