BDBM154545 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UNC2170, 1)
SMILES CC(C)(C)NCCCNC(=O)c1cccc(Br)c1
InChI Key InChIKey=XUFUVCIZFNREBI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 154545
Affinity DataIC50: 2.90E+4nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University of North Carolina At Chapel Hill
University of North Carolina At Chapel Hill
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Competitive displacement of p53K382me2 from His-tagged 53BP1 tandem Tudor domain (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase UHRF1(Homo sapiens (Human))
University of North Carolina At Chapel Hill
University of North Carolina At Chapel Hill
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Homo sapiens (Human))
University of North Carolina At Chapel Hill
University of North Carolina At Chapel Hill
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
TargetMBT domain-containing protein 1(Homo sapiens (Human))
University of North Carolina At Chapel Hill
University of North Carolina At Chapel Hill
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
Affinity DataKd: 2.20E+4nMpH: 8.0 T: 2°CAssay Description:All ITC measurements were recorded at 25 °C with an AutoITC200 microcalorimeter (MicroCal Inc.). All protein and compound stock samples were in the t...More data for this Ligand-Target Pair
Affinity DataKd: 2.20E+4nMAssay Description:Binding affinity to 53BP1 methyllysine binding domain (unknown origin) by ITC methodMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair