BDBM155526 US9012461, 2

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(c(CCc3cccc(c3)C(N)=O)n2)C(F)(F)F)cc1

InChI Key InChIKey=WOSZOOACNOXCKG-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155526   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155526(US9012461, 2)
Affinity DataIC50:  2.5nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155526(US9012461, 2)
Affinity DataIC50:  120nMpH: 7.0Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155526(US9012461, 2)
Affinity DataKd:  1.5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In DepthDetails US Patent