BDBM161587 US9108983, Example 402::US9108983, Example 403

SMILES Cc1c(cc(-c2cc(F)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n1C)C(=O)N(c1cnn(c1)[C@H]1CCOC1)c1ccc(O)cc1

InChI Key InChIKey=XJOFGWJUEHAPBP-LQJZCPKCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161587   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM161587(US9108983, Example 402 | US9108983, Example 403)
Affinity DataIC50:  24.2nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM161587(US9108983, Example 402 | US9108983, Example 403)
Affinity DataIC50:  26.1nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In DepthDetails US Patent