BDBM181019 US9133183, Example 15
SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCN(C4CCCCC4)C3=O)nc2)ccn1
InChI Key InChIKey=KFDMABXQUQMQTQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 181019
TargetMacrophage colony-stimulating factor 1 receptor [538-972](Homo sapiens (Human))
Deciphera Pharmaceuticals
US Patent
Deciphera Pharmaceuticals
US Patent
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Deciphera Pharmaceuticals
US Patent
Deciphera Pharmaceuticals
US Patent
Affinity DataIC50: 670nMT: 2°CAssay Description:These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMT: 2°CAssay Description:These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...More data for this Ligand-Target Pair