BDBM181208 US9139529, 51::US9783501, Compound 51

SMILES COc1cc(F)ccc1Oc1nc2ccccc2nc1C(=O)Nc1ccc(nc1)C#N

InChI Key InChIKey=DWLARPPEZGCACN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181208   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181208(US9139529, 51 | US9783501, Compound 51)
Affinity DataIC50:  37nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181208(US9139529, 51 | US9783501, Compound 51)
Affinity DataIC50:  37nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent