BDBM181208 US9139529, 51::US9783501, Compound 51
SMILES COc1cc(F)ccc1Oc1nc2ccccc2nc1C(=O)Nc1ccc(nc1)C#N
InChI Key InChIKey=DWLARPPEZGCACN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 181208
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataIC50: 37nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataIC50: 37nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair